Electron microscopy studies have shown that there is a continuum of shapes between these categories. The most notable classes of spine shape are "thin", "stubby", "mushroom", and "bifurcated". Spines with strong synaptic contacts typically have a large spine head, which connects to the dendrite via a membranous neck. Structure ĭendritic spines are small with spine head volumes ranging 0.01 μm 3 to 0.8 μm 3. It has also been suggested that changes in the activity of neurons have a positive effect on spine morphology. In addition to spines providing an anatomical substrate for memory storage and synaptic transmission, they may also serve to increase the number of possible contacts between neurons. The dendrites of a single neuron can contain hundreds to thousands of spines. Most spines have a bulbous head (the spine head), and a thin neck that connects the head of the spine to the shaft of the dendrite. Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body. A dendritic spine (or spine) is a small membranous protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.
0 kommentar(er)
